Reverse genetic platform for inactivated and live-attenuated influenza vaccine
نویسندگان
چکیده
منابع مشابه
Seasonal Effectiveness of Live Attenuated and Inactivated Influenza Vaccine.
BACKGROUND Few observational studies have evaluated the relative effectiveness of live attenuated (LAIV) and inactivated (IIV) influenza vaccines against medically attended laboratory-confirmed influenza. METHODS We analyzed US Influenza Vaccine Effectiveness Network data from participants aged 2 to 17 years during 4 seasons (2010-2011 through 2013-2014) to compare relative effectiveness of L...
متن کاملInfluenza Vaccination Strategies: Comparing Inactivated and Live Attenuated Influenza Vaccines
Influenza is a major respiratory pathogen causing annual outbreaks and occasional pandemics. Influenza vaccination is the major method of prophylaxis. Currently annual influenza vaccination is recommended for groups at high risk of complications from influenza infection such as pregnant women, young children, people with underlying disease and the elderly, along with occupational groups such a ...
متن کاملLive attenuated and inactivated influenza vaccines in children.
BACKGROUND Live attenuated influenza vaccine (LAIV) and inactivated influenza vaccine (IIV) are available for children. Local and systemic immunity induced by LAIV followed a month later by LAIV and IIV followed by LAIV were investigated with virus recovery after LAIV doses as surrogates for protection against influenza on natural exposure. METHODS Fifteen children received IIV followed by LA...
متن کاملLive attenuated influenza vaccine--a review.
Owing to the variability of influenza viruses, vaccine composition needs to be up-dated annually. As many variables can influence their efficacy, vaccines are still considered "sub-optimal". Many studies have been carried out in recent years to improve vaccines. In particular, researchers and vaccine-producing corporations have focused on developing a live vaccine. Among the candidate vaccines,...
متن کاملLive attenuated versus inactivated influenza vaccine in infants and young children.
BACKGROUND Universal vaccination of children 6 to 59 months of age with trivalent inactivated influenza vaccine has recently been recommended by U.S. advisory bodies. To evaluate alternative vaccine approaches, we compared the safety and efficacy of intranasally administered live attenuated influenza vaccine with those of inactivated vaccine in infants and young children. METHODS Children 6 t...
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ژورنال
عنوان ژورنال: Experimental and Molecular Medicine
سال: 2010
ISSN: 1226-3613
DOI: 10.3858/emm.2010.42.2.013